博士 教授 硕士生导师
通讯地址：北京市海淀区阜成路33号 北京工商大学理学院
邮编：100048
电子信箱：jinjianming@btbu.edu.cn
电话：010-68984917
个人简历：
1993年毕业于武汉大学生命科学学院生物化学专业，获理学学士学位；
1997年毕业于武汉大学生命科学学院生物化学专业，获理学硕士学位；
2002年毕业于中国科学院昆明植物研究所植物化学专业，获理学博士学位；
1993年至1994年在浙江永宁药业股份有限公司工作；
1997年至1999年中国科学院水生生物研究所工作；
2002年至2009年在韩国首尔大学农学与生命科学学院从事研究工作；
2009年至2010年在香港浸会大学生物学从事研究工作；
2010年至2011年在美国奥克拉荷马大学从事研究研究；
2011年至2012年在云南民族大学化学与生物技术学院工作；
2012年至今在北京工商大学理学院工作。
主要研究领域：
植物原料活性成分及其功效评价，活性成分的生物合成及其功效评价。
主要研究内容：
1.化妆品植物原料的提取分离工艺和功能性活性成分研究
2.植物原料的生物转化技术研究
3.基因工程高效合成活性成分及其功效评价研究
4.芦荟产品的质量安全研究
主要学术成就：
现主持二项国家自然科学基金和一项北京市自然科学基金。
发表论文：
1.Wei Chen, Jun Yao, Jie Meng, Wenjing Han, Yong Tao, Yihua Chen, Yixin Guo, Guizhi Shi, Yang He, Jian-Ming Jin* and Shuang-Yan Tang*. Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis. Nature Communications, 2019, 10: 960.
2.Chen Wei, Zhang Xuanxuan, Xiong Dandan, Jin Jian-Ming* and Tang Shuang-Yan*. Engineering the effector specificity of regulatory proteins for the in vitro detection of biomarkers and pesticide residues. Applied Microbiology and Biotechnology, 2019, 103(7): 3205–3213.
3.Heng Li, Jing Li, Ruinan Jin, Wei Chen, Chaoning Liang, Jieyuan Wu, Jian-Ming Jin, Shuang-Yan Tang*. Towards the construction of high-quality mutagenesis libraries. Biotechnology Letter, 2018, 40: 1101–1107.
4.Heng Li, Wei Chen, Rui-Nan Jin,Jian-Ming Jin*, Shuang-Yan Tang*. Biosensor‑aided high‑throughput screening of hyper‑producing cells for malonyl‑CoA‑derived products. Microbial Cell Factories, 2017, 16: 187.
5.Heng Li, Chaoning Liang, Wei Chen, Jian-Ming Jin*, Shuang-Yan Tang*, Yong Tao. Monitoring in vivo metabolic flux with a designed whole-cell metabolitebiosensor of shikimic acid. Biosensors and Bioelectronics, 2017, 98: 457–465.
6.Jieyuan Wu, Peixia Jiang, Wei Chen, Dandan Xiong, Linglan Huang, Junying Jia, Yuanyuan Chen, Jian-Ming Jin*, Shuang-Yan Tang*. Design and application of a lactulose biosensor. Scientific Reports, 2017, 7: 45994.
7.Dandan Xiong, Shikun Lua, Jieyuan Wu, Chaoning Liang, Wei Wang, Wenzhao Wang, Jian-Ming Jin*, Shuang-Yan Tang*. Improving key enzyme activity in phenylpropanoid pathway with a designed biosensor. Metabolic Engineering, 2017, 40: 115-123.
8.You-Hai Li, Wen-Jin Han, Xi-Wu Gui, Tao Wei, Shuang-Yan Tang, Jian-Ming Jin*. Putative nonribosomal peptide synthetase and cytochrome P450 genes responsible for tentoxin biosynthesis in Alternaria alternata ZJ33. Toxins, 2016, 8: 234.
9.Chaoning Liang, Yi Zhang, Yan Jia, Wenzhao Wang, Youhai Li, Shikun Lu, Jian-Ming Jin*, Shuang-Yan Tang*. Engineering a carbohydrate-processing transglycosidase into glycosyltransferase for natural product glycodiversification. Scientific Reports, 2016, 6: 21051.
10.Lin Zhu, Zhe Wu, Jian-Ming Jin, Shuang-Yan Tang*. Directed evolution of leucine dehydrogenase for improved efficiency of l-tert-leucine synthesis. Applied Microbiology and Biotechnology, 2016, 100: 5805–5813.
11.Peixia Jiang, Shanshan Mu, Heng Li, Youhai Li, Congmin Feng, Jian-Ming Jin* and Shuang-Yan Tang*. Design and application of a novel high-throughput screening technique for 1-deoxynojirimycin. Scientific Reports, 2015, 5: 8563.
12.Hokyoung Son, Young-Su Seo, Kyunghun Min, Ae Ran Park, Jungkwan Lee, Jian-Ming Jin, Yang Lin, Peijian Cao, Sae-Yeon Hong, Eun-Kyung Kim, Seung-Ho Lee, Aram Cho, Seunghoon Lee, Myunggu Kim, Yongsoo Kim, Jung-Eun Kim, Jin-Cheol Kim, Gyung Ja Choi, Sung-Hwan Yun, Jae Yun Lim, Minkyun Kim, Yong-Hwan Lee, Yang-Do Choi, Yin-Won Lee*. A phenome-based functional analysis of transcription factors in the cereal head blight Fungus, Fusarium graminearum. PLoS Pathogens, 2011, 7: e1002310.
13.Jian-Ming Jin, Seunghoon Lee, Jungkwan Lee, Seung-Ryul Baek, Jin-Cheol Kim, Sung-Hwan Yun, Sook-Toung Park, Seogchan Kang and Yin-Won Lee*. Functional characterization and manipulation of the apicidin biosynthetic pathway in Fusarium semitectum. Molecular Microbiology. 2010, 76: 456-466.
14.Jian-Ming Jin, Jung-Kuan Lee and Yin-Won Lee*. Characterization of the carotenoid biosynthetic genes in the ascomycete Gibberella zeae. FEMS Microbiology Letters. 2010, 320: 197-202.
15.Ju-Young Park, Jianming Jin, Yin-Won Lee, Seogchan Kang, and Yong-Hwan Lee*. Rice blast fungus Magnaporthe oryzae infects Arabidopsis thaliana via a distinct mechanism from that required for the infection of rice. Plant Physiology, 2009, 149: 474-486.
16.Jianming Jin, Seung-Ryul Baek, Kyung-Rim Lee, Jung-kwan Lee, Sung-Hwan Yun, Seogchan Kang and Yin-Won Lee*. Purification and phytotoxicity of apicidins produced by the Fusarium semitectum KCTC16676. The Plant Pathology Journal, 2008, 24: 385-388.
17.Jung-Eun Kim, Jin-Cheol Kim, Jianming Jin, Sung-Hwan Yun and Yin-Won Lee*. Functional characterization of genes located at the aurofusarin biosynthesis gene cluster in Gibberella zeae. The Plant Pathology Journal, 2008, 24: 8-16.
18.Jung-Eun Kim, Jianming Jin, Hun Kim, Jin-Cheol Kim, Sung-Hwan Yun, and Yin-Won Lee*. GIP2, a Putative Transcription Factor That Regulates the Aurofusarin Biosynthetic Gene Cluster in Gibberella zeae. Applied and Environmental Microbiology, 2006, 72: 1645-1652.
19.Yong-Tae Kim, Ye-Ryun Lee, Jianming Jin, Kap-Hoon Han, Hun Kim, Jin-Cheol Kim, Theresa Lee, Sung-Hwan Yun, and Yin-Won Lee*. Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae. Molecular Microbiology, 2005, 58: 1102–1113.
20.Jung-Eun Kim, Kap-Hoon Han, Jianming Jin, Hun Kim, Jin-Cheol Kim, Sung-Hwan Yun and Yin-won Lee*. Putative polyketide synthase and laccase genes for biosynthesis of aurofusarin in Gibberella zeae. Applied and Environmental Microbiology, 2005, 71: 1701-1708.
21.Yung-Jin Chang, Jian-Ming Jin, Hee-Young Nam and Soo-Un Kim*. Point mutation of (+)-germacrene A synthase from Ixeris dentate. Biotechnology Letters, 2005, 27: 285-288.
22.Min-Young Kim, Yung-Jin Chang, Myun-Ho Bang, Nam-In Baek, Jian-Ming Jin, Cheol-Ho Lee and Soo-Un Kim*. cDNA isolation and characterization of (+)-germacrene A synthase from Ixeris dentate form. Albiflora Hara. Journal of Plant Biology, 2005, 48: 178-186.
23.Jian-Ming Jin, Yin-Jun Zhang, Hai-zhou Li and Chong-ren Yang*. Cytotoxic steroidal saponins from Polygonatum zanlanscianense. Journal of Natural Products, 2004, 67: 1992-1995.
24.Jian-Ming Jin, Ying-Jun Zhang, and Chong-Ren Yang*. Four new steroid constituents from the waste residue of fibre separation from Agave americana leaves. Chemical & Pharmaceutical Bulletin, 2004, 52: 654-658.
25.Jian-Ming Jin, Ying-Jun Zhang, and Chong-Ren Yang*. Spirostanol and furostanol glycosides from the fresh tubers of Polianthes tuberosa. Journal of Natural Products, 2004, 67: 5-9.
26.Jian-Ming Jin, Xi-Kui Liu, and Chong-Ren Yang*. Three new hecogenin glycosides from fermented leaves of Agave americana. Journal of Asian natural products Research, 2003, 5: 95-103.
27.Jianming Jin, and Chongren Yang*. Two new steroidal sapogenins from fermented leaves of Agave americana. Chinese Chemical Letters, 2003, 14: 491-494.
28.Jianming Jin, Xikui Liu, and Chongren Yang*. A new cholestane glycoside from the tubers of Polianthes tuberosa. Acta Botanica Yunnanica, 2003, 25: 107-110.
29.JIN Jian-Ming, LIU Xi-kui, TENG Rong-Wei and YANG Chong-Ren*. Enzymatic degradation of parvifloside. Acta Botanica Sinica, 2002, 44: 1243-1249.
30.Jianming Jin, Xikui Liu, Rongwei Teng and Chongren Yang*. Two new steroidal glycosides from fermented leaves of Agave americana. Chinese Chemical Letters, 2002, 13: 629-632.
31.Jianming Jin, Xikui Liu, and Chongren Yang*. A new steroidal saponin from fermented leaves of Agave americana. Acta Botanica Yunnanica, 2002, 24: 539-542.
32.Jianming Jin, Xikui Liu, and Chongren Yang*. A new pregnane glycoside from fermented leaves of Agave americana. Chinese Chemical Letters, 2002, 13: 1189-1192.
